10 evidence based health benefits of ginger root, dosage and side effects


Zingiber officinale (ginger) belongs to Zingiberaceae family a close relative to turmeric. Ginger is consumed worldwide as a spice as well as herbal medicine. Due to its unique flavor and fragrance ginger is also used as a spice and flavoring agent in food. Apart from such use science had found numbers of health beneficial effects of ginger. So let’s find top 10 evidence based health benefits of ginger root along with daily dosage and side effects. Some of you may know but some of you may not. Let’s go through.

Besides its use as food additive ginger root also serves as an excellent source of several bio-active phenolics compounds, such as gingerols, paradols, shogaols, and gingerones. Inflammation and oxidative cell damages are two leading factors in development of chronic diseases. Bio-active compound of ginger exhibit a variety of biological activities including anti-inflammation, and anti-oxidation. Ginger also may act as a promoter of gastro intestinal integrity and bronchodilator.(1,2,3)

10 evidence based health benefits of ginger root, dosage and side effects

Help to relieve from Nausea

Research showed ginger helps to reduce nausea without risk of adverse effect. Symptoms like nausea is common in pregnancy, post surgery as well as in chemotherapy. In a systematic review and meta-analysis on 1278 pregnant women, 1.1-1.5 grams ginger significantly improved the symptoms of nausea. (4) In an another meta analysis ginger had also shown to reduce nausea as well as vomiting in patient after post surgery. (5) Other studies also showed ginger had reduced chemotherapy-induced nausea and vomiting. (6,7) This especially applies to morning sickness.

Can help to improve digestion

Digestive health contributes to overall health. Dyspepsia is a stomach problem with malfunctioning of the digestive system. In study published in the World Journal of Gastroenterology ginger stimulated gastric emptying and antral contractions that improves moving of food through gastro intestinal tract in patients with functional dyspepsia. Researcher used 1200 mg ginger in that study. (8) In an another study on 24 healthy people taking 1200 mg of ginger root powder before meal accelerated gastric emptying and stimulates antral contractions. (9) Other studies also showed that ginger had stimulated antral contractions as well as reduced delayed gastric emptying. (10,11,12)

Reduce Muscle pain

Ginger has anti inflammatory as well as analgesic properties. Although it may not have immediate effect research showed that ginger may reduce the day-to-day progression of exercise induced muscle pain. (13)Another systematic review of 7 randomized trials had found while ginger taken over 1-2 weeks may reduce pain from eccentric resistance exercise and prolonged running. Their evidence indicates that roughly 2 g per day of ginger may modestly reduce muscle pain originated from resistance exercise as well as prolonged running. (3)

10 evidence based health benefits of ginger root, dosage and side effects

Can help in reducing Menstrual Pain, bleeding  

For many women pain, bleeding are common in menstruation period. Research showed that ginger effectively reduced menstrual pain. (14) A Randomized Controlled Trails had also shown with five day ginger intake significantly reduce intensity as well as duration of pain. Researcher used 500 mg capsule of ginger root powder three times a day in the study with ginger treated group. (15)

In an another, placebo-controlled, double-blind, randomized trial, had conducted on 92 high school girls with heavy menstrual bleeding. They were examined for 6 consecutive menstrual cycles. They observed level of menstrual blood loss dramatically declined by 46.6% during the three intervention cycles in ginger-receiving group compared with the 3 pre-intervention assessment cycles. Researchers also reported that minimum number of participants had reported adverse effects.(16)

This appears to affect when taken at the beginning of menstruation.

Help to fight infection

Numbers of studies had also shown ginger has effective antibacterial activity against different types of pathogenic bacteria. (17,18,19) Ginger has not only antibacterial activity but also had shown anti-fungal activity against a wide variety of fungi in vitro or test tube. (20, 21) Therefore with such antibacterial anti inflammation as well as antifungal properties ginger can help to fight against infection.

May improve brain health

We already mentioned above that oxidative stress and chronic inflammation are leading factors in premature aging as well as development of many diseases. In study bio-active compound of ginger appears to inhibit inflammation in brain. (22) Another study also demonstrates that ginger extract enhances both attention and cognitive function in healthy, middle-aged women, with no side effects reported. (23) Other study also reported ginger protects age related mental decline. (24)

Related article:

Bacopa Monnieri is a powerful herbs for brain health and functions like memory, cognitive and also shown protective against Alzheimer’s.

Blood sugar regulation

Abnormal blood sugar level can relates with many health hazards including heart disease, obesity, metabolic syndrome and also many others. Ginger appears to normalize blood sugar. In animal study ginger had reduced blood glucose level. Although more data is not available one randomized, double blind, placebo controlled clinical trial reported ginger had reduced fasting blood sugar by around 12% in both men and women. And they also observed improvement in t blood sugar control by 10% over a period of 12 weeks. They also concluded that with negligible side effects of ginger, it may be a good remedy for diabetic patients. (25)


Although have limitation of not being double blind a study found significant results. Researcher observed ginger had increased testosterone(by 17.7%) luteinizing hormone(by 43.2%) that controls reproductive system, sperm count (by 16.2%) as well as ejaculate volume(by 36.1%)  in men. The study also noted improvement of antioxidant profile with increase of serum glutathione concentration(by 26.7%) (26)

May help to lower cholesterol number

High level of LDL, triglycerides is not a desirable condition especially for cardiovascular health. Ginger administration also had shown to reduce triglyceride, cholesterol, low density lipoprotein (LDL). And thus improves lipid parameters.(27) However these reductions may not to a large extent.

May help to prevent cancer

Some studies also reported ginger may prevent growth of cancer cell in some cases like ovarian cancer, pancreatic, prostate cancer, colon cancer.(28,29,30,31)


Dosages ranged from 250 mg to 2 g/day given in 3 to 4 divided doses.(32,33,34, 35)

Also read about incredible health benefits of mighty turmeric or curcumin as well as therapeutic dosage.

What do we know about risk or safety

One corhot study from 1020 women using ginger during pregnancy concluded  use of ginger during pregnancy does not seem to increase the risk of congenital malformations, stillbirth/perinatal death, preterm birth, low birth weight, as well as low health score of new born.(36)

The US Food and Drug Administration (FDA) lists ginger as generally recognized as safe.(37) However large dose may carry potential adverse reaction like stomach upset, mouth irritation or other similar. Ginger can also slower blood clotting. Hence people with taking blood clotting medication should consult with health care provider.

However due to high soluble oxalate content of ginger people with tendency of developing kidney stone should avoid ginger. Apart from that individual with unhealthy gut or increased intestinal permeability should avoid food with high oxalates more specifically soluble oxalate. (38)

Bottom line

There is a long use of ginger root worldwide. Although very large data is not available ginger had showed multiple benefits in well designed studies. Ginger root appears as safe when use within recommend dose. However be careful about adulterated product. Ginger root can enhance flavor of food and has different usage. As example you can add with food, can drink with warm water, prepare with tea, and also can take supplement. Being an small plant you can even grow ginger in a pot.

Disclaimer: Information provided here are generalized information for 
educational purpose only,  not intended to provide one to one health 
consultation or replace practice of a qualified practitioner. Different 
people may have different health condition and may have different reaction 
to the same food. Hence it has been advised to consult with health care 
provider before application of any of above guidelines.  
Source and References:
1.Wang S, Zhang C, Yang G, Yang Y.,Biological properties of 6-gingerol: a 
brief review,Nat Prod Commun. 2014 Jul;9(7):1027-30
2.Zhang F, Thakur K, Hu F, Zhang JG, Wei ZJ,Cross-talk between 10-gingerol 
and its anti-cancerous potential: a recent update,Food Funct. 2017 Aug 
3.Wilson PB.,Ginger (Zingiber officinale) as an Analgesic and Ergogenic Aid 
in Sport: A Systemic Review,J Strength Cond Res. 2015 Oct;29(10):2980-95 
4.Estelle Viljoen, Janicke Visser, Nelene Koen, and  Alfred Musekiwa,
A systematic review and meta-analysis of the  effect and safety of ginger 
in the treatment of pregnancy-associated  nausea and vomiting,Nutr J. 2014; 
13: 20
5.Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, Leeprakobboon K, 
Leelasettagool C.,The efficacy of ginger for the prevention of 
postoperative nausea and vomiting: a meta-analysis,Am J Obstet Gynecol. 
2006 Jan;194(1):95-9      
6.Pillai AK, Sharma KK, Gupta YK, Bakhshi S.,Anti-emetic effect of ginger 
powder versus placebo as an add-on  therapy in children and young adults 
receiving high emetogenic  chemotherapy,Pediatr Blood Cancer. 2011 
7.Ryan JL, Heckler CE, Roscoe JA, Dakhil SR, Kirshner J, Flynn PJ, Hickok 
JT, Morrow GR.,Ginger (Zingiber officinale) reduces acute chemotherapy-
induced nausea: a URCC CCOP study of 576 patients,Support Care Cancer. 2012 
8.Ming-Luen Hu, Christophan K Rayner, Keng-Liang Wu, Seng-Kee Chuah, Wei-
Chen Tai, Yeh-Pin Chou, Yi-Chun Chiu, King-Wah Chiu, and  Tsung-Hui Hu,
Effect of ginger on gastric motility and symptoms of functional dyspepsia,
World J Gastroenterol. 2011 Jan 7; 17(1): 105–110
9.Wu KL, Rayner CK, Chuah SK, Changchien CS, Lu SN, Chiu YC, Chiu KW, Lee 
CM.,Effects of ginger on gastric emptying and motility in healthy humans.,
Eur J Gastroenterol Hepatol. 2008 May;20(5):436-40.
10.Wu KL, Rayner CK, Chuah SK, Changchien CS, Lu SN, Chiu YC, Chiu KW, Lee 
CM.,Effects of ginger on gastric emptying and motility in healthy humans,
Eur J Gastroenterol Hepatol. 2008 May;20(5):436-40
11.Shariatpanahi ZV, Taleban FA, Mokhtari M, Shahbazi S.,Ginger extract 
reduces delayed gastric emptying and nosocomial  pneumonia in adult 
respiratory distress syndrome patients hospitalized  in an intensive care 
unit,J Crit Care. 2010 Dec;25(4):647-50.  
12.Hu ML, Rayner CK, Wu KL, Chuah SK, Tai WC, Chou YP, Chiu YC, Chiu KW, Hu 
TH., Effect of ginger on gastric motility and symptoms of functional 
dyspepsia,World J Gastroenterol. 2011 Jan 7;17(1):105-10
13.Black CD, O'Connor PJ.,Acute effects of dietary ginger on muscle pain 
induced by eccentric exercise,Phytother Res. 2010 Nov;24(11):1620-6
14.Ozgoli G, Goli M, Moattar F.,Comparison of effects of ginger, mefenamic 
acid, and ibuprofen on pain in women with primary dysmenorrhea,J Altern 
Complement Med. 2009 Feb;15(2):129-32 
15.Parvin Rahnama, Ali Montazeri, Hassan Fallah Huseini, Saeed Kianbakht, 
and Mohsen Naseri,Effect of Zingiber officinale R. rhizomes (ginger) on 
pain relief in primary dysmenorrhea: a placebo randomized trial, BMC 
Complement Altern Med. 2012; 12: 92. 
16. Kashefi F, Khajehei M, Alavinia M, Golmakani E, Asili J.,Effect of 
ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-
controlled, randomized clinical trial,Phytother Res. 2015 Jan;29(1):114-9
17.Ponmurugan Karuppiah and  Shyamkumar Rajaram,Antibacterial effect of 
Allium sativum cloves and Zingiber officinale rhizomes against multiple-
drug resistant clinical pathogens,Asian Pac J Trop Biomed. 2012 Aug; 2(8): 
18.Gull I, Saeed M, Shaukat H, Aslam SM, Samra ZQ, Athar AM.,Inhibitory 
effect of Allium sativum and Zingiber officinale extracts on clinically 
important drug resistant pathogenic bacteria,Ann Clin Microbiol Antimicrob. 
2012 Apr 27;11:8 
19.Iram Gull,Mariam Saeed, Halima Shaukat, Shahbaz M Aslam, Zahoor Qadir 
Samra, and  Amin M Athar,Inhibitory effect of Allium sativum and Zingiber 
officinale extracts on clinically important drug resistant pathogenic 
bacteria, Ann Clin Microbiol Antimicrob. 2012; 11: 8
20.Aghazadeh M, Zahedi Bialvaei A, Aghazadeh M, Kabiri F, Saliani N, 
Yousefi M, Eslami H, Samadi Kafil H.,Survey of the Antibiofilm and 
Antimicrobial Effects of Zingiber officinale (in Vitro Study),Jundishapur J 
Microbiol. 2016 Feb 7;9(2):e30167    
21.Ficker CE1, Arnason JT, Vindas PS, Alvarez LP, Akpagana K, Gbéassor M, 
De Souza C, Smith ML.,Inhibition of human pathogenic fungi by 
ethnobotanically selected plant extracts, Mycoses. 2003 Feb;46(1-2):29-37
22.Faizul Azam, Abdualrahman M Amer, Abdullah R Abulifa, and  Mustafa M 
Elzwawi,Ginger components as new leads for the design  and development of 
novel multi-targeted anti-Alzheimer’s drugs: a  computational 
investigation,Drug Des Devel Ther. 2014; 8: 2045–2059
23.Naritsara Saenghong, Jintanaporn Wattanathorn, Supaporn Muchimapura, 
Terdthai Tongun, Nawanant Piyavhatkul, Chuleratana Banchonglikitkul, and  
Tanwarat Kajsongkram,Zingiber officinale Improves Cognitive Function of the 
Middle-Aged Healthy Women,Evid Based Complement Alternat Med. 2012; 2012: 
24.Wattanathorn J, Jittiwat J, Tongun T, Muchimapura S, Ingkaninan K.,
Zingiber officinale Mitigates Brain Damage and Improves Memory Impairment 
in Focal Cerebral Ischemic Rat.,Evid Based Complement Alternat Med. 
25.Nafiseh Khandouzi, Farzad Shidfar, Asadollah Rajab, Tayebeh Rahideh, 
Payam Hosseini, and  Mohsen Mir Taheri,The Effects of Ginger on Fasting 
Blood Sugar,  Hemoglobin A1c, Apolipoprotein B, Apolipoprotein A-I and 
Malondialdehyde  in Type 2 Diabetic Patients,Iran J Pharm Res. 2015 Winter; 
14(1): 131–140 
26. Waleed Abid Al-Kadir Mares, Wisam S. Najam,The effect of Ginger on 
semen parameters and serum FSH, LH & Testosterone of infertile men,
Tikrit Medical Journal 2012;18(2):322-329
27.Alizadeh-Navaei R, Roozbeh F, Saravi M, Pouramir M, Jalali F, 
Moghadamnia AA.,Investigation of the effect of ginger on the lipid levels. 
A double blind controlled clinical trial,Saudi Med J. 2008 Sep;29(9):1280-4
28.Jennifer Rhode, Sarah Fogoros, Suzanna Zick, Heather Wahl, Kent A 
Griffith, Jennifer Huang, and  J Rebecca Liu,Ginger inhibits cell growth 
and modulates angiogenic factors in ovarian cancer cells,BMC Complement 
Altern Med. 2007; 7: 44 
29.Karna P, Chagani S, Gundala SR, Rida PC, Asif G, Sharma V, Gupta MV, 
Aneja R.,Benefits of whole ginger extract in prostate cancer,Br J Nutr. 
2012 Feb;107(4):473-84   
30.Yon Jung Park, Jing Wen, Seungmin Bang, Seung Woo Park, and  Si Young 
Song,[6]-Gingerol Induces Cell Cycle Arrest and Cell Death of Mutant p53-
expressing Pancreatic Cancer Cells, Yonsei Med J. 2006 Oct 31; 47(5): 688–
31.Lee SH, Cekanova M, Baek SJ.,Multiple mechanisms are involved in 6-
gingerol-induced cell growth arrest and apoptosis in human colorectal 
cancer cells,Mol Carcinog. 2008 Mar;47(3):197-208 
32.Chrubasik S, Pittler MH, Roufogalis BD. Zingiberis rhizoma: a 
comprehensive review on the ginger effect and efficacy profiles. 
Phytomedicine. 2005;12(9):684-701.16194058
33.Yu Y, Zick S, Li X, Zou P, Wright B, Sun D. Examination of the 
pharmacokinetics of active ingredients of ginger in humans. AAPS J. 
34.White B. Ginger: an overview. Am Fam Physician. 2007;75(11):1689-
35.Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, Leeprakobboon K, 
Leelasettagool C. The efficacy of ginger for the prevention of 
postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol. 
36. Heitmann K, Nordeng H, Holst L.,Safety of ginger use in pregnancy: 
results from a large population-based cohort study,Eur J Clin Pharmacol. 
2013 Feb;69(2):269-77 
38.Sumana Ghosh Das,Geoffrey Peter Savage,Total and Soluble Oxalate Content 
of Some Indian Spices,Plant Foods for Human Nutrition 67(2):186-90 · April 
Bikramjit Konwar

Author: Bikramjit Konwar


4 Responses

  1. Ginger has certain beneficial effect in improving sore throat in cough and cold. But other effects needs to be verified in controlled clinical trial. If 2.5 gm ginger is used in the trial, how much of active ingredient actually has gone in and which particular ingredient was of medicinal value?

    1. In most studies ginger was taken as power. With fresh ginger with water content requires more to have the same effect. Mostly ginger was tested as whole. The major phenolic compound that contains in ginger is gingerols. And percentage of phenolic compound also may vary with location, soil, climatic condition.
      Most data available here are from human studies including RCT, meta analysis
      Randomized, double blind, placebo controlled clinical trial are considered as gold standard with randomization, double blind and placebo effect. Meta analysis and systematic review are generally collection and analysis such RCT studies for bigger picture. These types of studies are highly valued studies in healthcare. Animal studies are given less valued only in some special cases.

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